Gut Feelings: Microbiome Insights in Anesthesia & Pain Management-Presentation Slides

Presentation Slides

Pdf Summary

Dr. Jiale Hu, an Assistant Professor at Virginia Commonwealth University, discusses the significant role of the gut microbiome in anesthesia and pain management in his work "Gut Feelings: Microbiome Insights in Anesthesia & Pain Management." In the document, Dr. Hu covers topics such as the history of medical microbiology, the human microbiome project, microbial dysbiosis, and the gut-brain axis. The complexity and diversity of the microbiota, along with the emergence of pharmacomicrobiomics, are also explored.<br /><br />The text delves into the interactions between the gut microbiome and anesthesia, as well as opioids, in perioperative settings. It highlights studies on how anesthetics and opioids impact the gut microbiota composition and the lasting effects on patients. The role of the gut microbiome in patient outcomes post-anesthesia, such as cognitive dysfunction and chronic pain, is emphasized.<br /><br />Dr. Hu suggests the integration of multi-omic techniques for microbiome analysis to tailor personalized anesthesia and address clinical questions in the field. The document also points out the potential exponential growth of the human microbiome market and various applications in clinical assessments, medication development, and disease prevention. Moreover, current findings on postoperative cognitive dysfunction and chronic postsurgical pain, and their relationship with the gut-brain axis, are discussed.<br /><br />Overall, the document underscores the importance of understanding the gut microbiome's influence on anesthesia outcomes and the potential for microbiome-based interventions to improve patient care and outcomes in surgical settings.

Keywords

gut microbiome

anesthesia

pain management

microbial dysbiosis

gut-brain axis

pharmacomicrobiomics

opioids

perioperative

postoperative cognitive dysfunction

personalized anesthesia